Marfan Syndrome is a genetic defect that has an autosomal dominant mode of transmission, it occurs in every three out of four people coming from either one of their parents, the child has a 50% chance of receiving the mutation, only needing one copy to develop the syndrome. While the parent and child may share the same mutation, they don't always have identical characteristics of the syndrome, the child could have spinal problems while the parent never did. For some children though the parents never had the mutated gene but instead a spontaneous mutation before the child's birth resulting in the development of Marfan Syndrome. Every unborn child has a 1 in 10,000 or .01% chance of developing the syndrome from spontaneous mutations.
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